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Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.



Selected by Pierre Caron

Actin-driven protrusions generate rapid long-range membrane tension propagation in cells

Henry De Belly, Shannon Yan, Hudson Borja da Rocha, et al.



Selected by Nicolaes Hyun-Kee Min

Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

AND

Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.



Selected by Monica Tambalo et al.

Periodic spatial patterning with a single morphogen

Sheng Wang, Jordi Garcia-Ojalvo, Michael B. Elowitz



Selected by Jake Cornwall-Scoones

Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism

Mírian Romitti, Barbara de Faria da Fonsecaa, Gilles Doumont, et al.



Selected by Anna Meier

Epicardial HDAC3 promotes myocardial growth through a novel microRNA pathway

Jihyun Jang, Guang Song, Qinshan Li, et al.



Selected by Anna Meier

Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc

Ioannis Nellas, K. Venkatesan Iyer, Juan M. Iglesias-Artola, et al.



Selected by Julia Grzymkowski

Optogenetic control of apical constriction induces synthetic morphogenesis in mammalian tissues

Guillermo Martínez-Ara, Núria Taberner, Mami Takayama, et al.



Selected by Monica Tambalo

embryological manipulation to probe early evo-devo in the fish Astyanax mexicanus

Jorge Torres-Paz, Sylvie Rétaux



Selected by Paul Gerald L. Sanchez and Stefano Vianello

Small molecules exploiting structural differences within microRNA-200 precursors family members reverse a type 2 diabetes phenotype

Hafeez S. Haniff, Xiaohui Liu, Laurent Knerr, et al.



Selected by Zhang-He Goh

Cardioids reveal self-organizing principles of human cardiogenesis

Pablo Hofbauer, Stefan Jahnel, Nora Papai, et al.



Selected by Alok Javali

Replication protein A binds RNA and promotes R-loop formation

Olga M. Mazina, Srinivas Somarowthu, Lyudmila Y. Kadyrova, et al.



Selected by Giuseppina D'Alessandro
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